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B7H6-specific chimeric antigen receptors lead to tumor elimination and host anti-tumor immunity
Chimeric antigen receptor (CAR) T cell therapies have demonstrated durable and potentially curative therapeutic efficacy against B cell leukemia in clinical trials. A CAR strategy can target any tumor surface antigens as long as an antigen-binding receptor can be generated. New CARs which target sol...
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| Veröffentlicht in: | Gene Ther |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4529373/ https://ncbi.nlm.nih.gov/pubmed/25830550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2015.29 |
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