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Development of unique cytotoxic chimeric antigen receptors based on human scFv targeting B7H6
As a stress-inducible natural killer (NK) cell ligand, B7H6 plays a role in innate tumor immunosurveillance and is a fairly tumor selective marker expressed on a variety of solid and hematologic cancer cells. Here, we describe the isolation and characterization of a new family of single chain fragme...
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| Publicat a: | Protein Eng Des Sel |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5914360/ https://ncbi.nlm.nih.gov/pubmed/29040754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzx051 |
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