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Development of unique cytotoxic chimeric antigen receptors based on human scFv targeting B7H6

As a stress-inducible natural killer (NK) cell ligand, B7H6 plays a role in innate tumor immunosurveillance and is a fairly tumor selective marker expressed on a variety of solid and hematologic cancer cells. Here, we describe the isolation and characterization of a new family of single chain fragme...

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Bibliografiske detaljer
Udgivet i:Protein Eng Des Sel
Main Authors: Hua, Casey K, Gacerez, Albert T, Sentman, Charles L, Ackerman, Margaret E
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914360/
https://ncbi.nlm.nih.gov/pubmed/29040754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzx051
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