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B7H6-specific bispecific T cell engagers (BiTEs) lead to tumor elimination and host anti-tumor immunity(),2
Substantial evidence showed that T cells are the key effectors in immune-mediated tumor eradication. However, most T cells do not exhibit anti-tumor specificity. In this study, a bispecific T cell engager (BiTE) approach was utilized to direct T cells to recognize B7H6+ tumor cells. B7H6 is a specif...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Immunol |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433849/ https://ncbi.nlm.nih.gov/pubmed/25911747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402517 |
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