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B7H6-specific bispecific T cell engagers (BiTEs) lead to tumor elimination and host anti-tumor immunity(),2

Substantial evidence showed that T cells are the key effectors in immune-mediated tumor eradication. However, most T cells do not exhibit anti-tumor specificity. In this study, a bispecific T cell engager (BiTE) approach was utilized to direct T cells to recognize B7H6+ tumor cells. B7H6 is a specif...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Wu, Ming-Ru, Zhang, Tong, Gacerez, Albert T., Coupet, Tiffany A., DeMars, Leslie R., Sentman, Charles L.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433849/
https://ncbi.nlm.nih.gov/pubmed/25911747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402517
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