Generation of dual specific bivalent BiTEs (dbBIspecific T-cell engaging antibodies) for cellular immunotherapy

BACKGROUND: Bispecific T-cell engaging antibodies (BiTES), comprising dual anti-CD3 and anti-tumor antigen scFv fragments, are important therapeutic agents for the treatment of cancer. The dual scFv construct for BiTES requires proper protein folding while their small molecular size leads to rapid k...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:BMC Cancer
Asıl Yazarlar: Kujawski, Maciej, Li, Lin, Bhattacharya, Supriyo, Wong, Patty, Lee, Wen-Hui, Williams, Lindsay, Li, Harry, Chea, Junie, Poku, Kofi, Bowles, Nicole, Vaidehi, Nagarajan, Yazaki, Paul, Shively, John E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Technical Advance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727398/
https://ncbi.nlm.nih.gov/pubmed/31488104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6056-8
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller