Wird geladen...

The Prion Protein N1 and N2 Cleavage Fragments Bind to Phosphatidylserine and Phosphatidic Acid; Relevance to Stress-Protection Responses

Internal cleavage of the cellular prion protein generates two well characterised N-terminal fragments, N1 and N2. These fragments have been shown to bind to anionic phospholipids at low pH. We sought to investigate binding with other lipid moieties and queried how such interactions could be relevant...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Haigh, Cathryn L., Tumpach, Carolin, Drew, Simon C., Collins, Steven J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529310/
https://ncbi.nlm.nih.gov/pubmed/26252007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134680
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!