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The Prion Protein N1 and N2 Cleavage Fragments Bind to Phosphatidylserine and Phosphatidic Acid; Relevance to Stress-Protection Responses

Internal cleavage of the cellular prion protein generates two well characterised N-terminal fragments, N1 and N2. These fragments have been shown to bind to anionic phospholipids at low pH. We sought to investigate binding with other lipid moieties and queried how such interactions could be relevant...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Haigh, Cathryn L., Tumpach, Carolin, Drew, Simon C., Collins, Steven J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529310/
https://ncbi.nlm.nih.gov/pubmed/26252007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134680
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