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Prion protein cleavage fragments regulate adult neural stem cell quiescence through redox modulation of mitochondrial fission and SOD2 expression

Neurogenesis continues in the post-developmental brain throughout life. The ability to stimulate the production of new neurones requires both quiescent and actively proliferating pools of neural stem cells (NSCs). Actively proliferating NSCs ensure that neurogenic demand can be met, whilst the quies...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Collins, Steven J., Tumpach, Carolin, Groveman, Bradley R., Drew, Simon C., Haigh, Cathryn L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063333/
https://ncbi.nlm.nih.gov/pubmed/29574582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2790-3
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