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Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection

Oxidative stress as a contributor to neuronal death during prion infection is supported by the fact that various oxidative damage markers accumulate in the brain during the course of this disease. The normal cellular substrate of the causative agent, the prion protein, is also linked with protective...

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Bibliografiset tiedot
Päätekijät: Sinclair, Layla, Lewis, Victoria, Collins, Steven J., Haigh, Cathryn L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists Limited 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701215/
https://ncbi.nlm.nih.gov/pubmed/23580200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010678
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