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The analysis of clonal expansions in normal and autoimmune B cell repertoires

Clones are the fundamental building blocks of immune repertoires. The number of different clones relates to the diversity of the repertoire, whereas their size and sequence diversity are linked to selective pressures. Selective pressures act both between clones and within different sequence variants...

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Vydáno v:Philos Trans R Soc Lond B Biol Sci
Hlavní autoři: Hershberg, Uri, Luning Prak, Eline T.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528416/
https://ncbi.nlm.nih.gov/pubmed/26194753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0239
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