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The analysis of clonal expansions in normal and autoimmune B cell repertoires

Clones are the fundamental building blocks of immune repertoires. The number of different clones relates to the diversity of the repertoire, whereas their size and sequence diversity are linked to selective pressures. Selective pressures act both between clones and within different sequence variants...

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Detalles Bibliográficos
Publicado en:Philos Trans R Soc Lond B Biol Sci
Autores principales: Hershberg, Uri, Luning Prak, Eline T.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528416/
https://ncbi.nlm.nih.gov/pubmed/26194753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0239
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