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The analysis of clonal expansions in normal and autoimmune B cell repertoires

Clones are the fundamental building blocks of immune repertoires. The number of different clones relates to the diversity of the repertoire, whereas their size and sequence diversity are linked to selective pressures. Selective pressures act both between clones and within different sequence variants...

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Veröffentlicht in:Philos Trans R Soc Lond B Biol Sci
Hauptverfasser: Hershberg, Uri, Luning Prak, Eline T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528416/
https://ncbi.nlm.nih.gov/pubmed/26194753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0239
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