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The analysis of clonal expansions in normal and autoimmune B cell repertoires

Clones are the fundamental building blocks of immune repertoires. The number of different clones relates to the diversity of the repertoire, whereas their size and sequence diversity are linked to selective pressures. Selective pressures act both between clones and within different sequence variants...

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Pubblicato in:Philos Trans R Soc Lond B Biol Sci
Autori principali: Hershberg, Uri, Luning Prak, Eline T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528416/
https://ncbi.nlm.nih.gov/pubmed/26194753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0239
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