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The analysis of clonal expansions in normal and autoimmune B cell repertoires

Clones are the fundamental building blocks of immune repertoires. The number of different clones relates to the diversity of the repertoire, whereas their size and sequence diversity are linked to selective pressures. Selective pressures act both between clones and within different sequence variants...

Полное описание

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Библиографические подробности
Опубликовано в: :Philos Trans R Soc Lond B Biol Sci
Главные авторы: Hershberg, Uri, Luning Prak, Eline T.
Формат: Artigo
Язык:Inglês
Опубликовано: The Royal Society 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528416/
https://ncbi.nlm.nih.gov/pubmed/26194753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0239
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