Novel Allosteric Modulators of G Protein-coupled Receptors

G protein-coupled receptors (GPCRs) are allosteric proteins, because their signal transduction relies on interactions between topographically distinct, yet conformationally linked, domains. Much of the focus on GPCR allostery in the new millennium, however, has been on modes of targeting GPCR allost...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Gentry, Patrick R., Sexton, Patrick M., Christopoulos, Arthur
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528113/
https://ncbi.nlm.nih.gov/pubmed/26100627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.662759
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