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Novel Allosteric Modulators of G Protein-coupled Receptors

G protein-coupled receptors (GPCRs) are allosteric proteins, because their signal transduction relies on interactions between topographically distinct, yet conformationally linked, domains. Much of the focus on GPCR allostery in the new millennium, however, has been on modes of targeting GPCR allost...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Gentry, Patrick R., Sexton, Patrick M., Christopoulos, Arthur
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528113/
https://ncbi.nlm.nih.gov/pubmed/26100627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.662759
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