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Novel Allosteric Modulators of G Protein-coupled Receptors

G protein-coupled receptors (GPCRs) are allosteric proteins, because their signal transduction relies on interactions between topographically distinct, yet conformationally linked, domains. Much of the focus on GPCR allostery in the new millennium, however, has been on modes of targeting GPCR allost...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Gentry, Patrick R., Sexton, Patrick M., Christopoulos, Arthur
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528113/
https://ncbi.nlm.nih.gov/pubmed/26100627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.662759
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