Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice

BACKGROUND: Recent evidence indicates that inhibition of histone deacetylase (HDAC) protects the heart against myocardial injury and stimulates endogenous angiomyogenesis. However, it remains unknown whether HDAC inhibition produces the protective effect in the diabetic heart. We sought to determine...

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Dettagli Bibliografici
Pubblicato in:Cardiovasc Diabetol
Autori principali: Chen, Youfang, Du, Jianfeng, Zhao, Yu Tina, Zhang, Ling, Lv, Guorong, Zhuang, Shougang, Qin, Gangjian, Zhao, Ting C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527099/
https://ncbi.nlm.nih.gov/pubmed/26245924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0262-8
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