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Inhibition of Histone Deacetylases Preserves Myocardial Performance and Prevents Cardiac Remodeling through Stimulation of Endogenous Angiomyogenesis

We have previously shown that the inhibition of histone deacetylases (HDACs) protects the heart against acute myocardial ischemia and reperfusion injury. We also demonstrated that HDAC inhibition stimulates myogenesis and angiogenesis in a cultured embryonic stem cell model. We investigate whether i...

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Detalhes bibliográficos
Main Authors: Zhang, Ling, Qin, Xin, Zhao, Yu, Fast, Loren, Zhuang, Shougang, Liu, Paul, Cheng, Guangmao, Zhao, Ting C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310703/
https://ncbi.nlm.nih.gov/pubmed/22271820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.189910
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