Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice

BACKGROUND: Recent evidence indicates that inhibition of histone deacetylase (HDAC) protects the heart against myocardial injury and stimulates endogenous angiomyogenesis. However, it remains unknown whether HDAC inhibition produces the protective effect in the diabetic heart. We sought to determine...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Chen, Youfang, Du, Jianfeng, Zhao, Yu Tina, Zhang, Ling, Lv, Guorong, Zhuang, Shougang, Qin, Gangjian, Zhao, Ting C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527099/
https://ncbi.nlm.nih.gov/pubmed/26245924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0262-8
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