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Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice

BACKGROUND: Recent evidence indicates that inhibition of histone deacetylase (HDAC) protects the heart against myocardial injury and stimulates endogenous angiomyogenesis. However, it remains unknown whether HDAC inhibition produces the protective effect in the diabetic heart. We sought to determine...

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Bibliografiske detaljer
Udgivet i:Cardiovasc Diabetol
Main Authors: Chen, Youfang, Du, Jianfeng, Zhao, Yu Tina, Zhang, Ling, Lv, Guorong, Zhuang, Shougang, Qin, Gangjian, Zhao, Ting C
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527099/
https://ncbi.nlm.nih.gov/pubmed/26245924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0262-8
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