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Histone Deacetylase 4 (HDAC4): Mechanism of Regulations and Biological Functions

The acetylation and deacetylation of histones play an important role in the regulation of gene transcriptions. Histone acetylation is mediated by histone acetyltransferase (HAT). The resulting modification in the structure of chromatin leads to nucleosomal relaxation and altered transcriptional acti...

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Detalhes bibliográficos
Publicado no:Epigenomics
Main Authors: Wang, Zhengke, Qin, Gangjian, Zhao, Ting C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380265/
https://ncbi.nlm.nih.gov/pubmed/24579951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.13.73
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