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Histone Deacetylase 4 (HDAC4): Mechanism of Regulations and Biological Functions

The acetylation and deacetylation of histones play an important role in the regulation of gene transcriptions. Histone acetylation is mediated by histone acetyltransferase (HAT). The resulting modification in the structure of chromatin leads to nucleosomal relaxation and altered transcriptional acti...

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Bibliographic Details
Published in:Epigenomics
Main Authors: Wang, Zhengke, Qin, Gangjian, Zhao, Ting C.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380265/
https://ncbi.nlm.nih.gov/pubmed/24579951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.13.73
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