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Treatment of chronic kidney diseases with histone deacetylase inhibitors

Histone deacetylases (HDACs) induce deacetylation of both histone and non-histone proteins and play a critical role in the modulation of physiological and pathological gene expression. Pharmacological inhibition of HDAC has been reported to attenuate progression of renal fibrogenesis in obstructed k...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Liu, Na, Zhuang, Shougang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411966/
https://ncbi.nlm.nih.gov/pubmed/25972812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00121
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