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Inhibition of Histone Deacetylases Preserves Myocardial Performance and Prevents Cardiac Remodeling through Stimulation of Endogenous Angiomyogenesis

We have previously shown that the inhibition of histone deacetylases (HDACs) protects the heart against acute myocardial ischemia and reperfusion injury. We also demonstrated that HDAC inhibition stimulates myogenesis and angiogenesis in a cultured embryonic stem cell model. We investigate whether i...

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Autori principali: Zhang, Ling, Qin, Xin, Zhao, Yu, Fast, Loren, Zhuang, Shougang, Liu, Paul, Cheng, Guangmao, Zhao, Ting C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310703/
https://ncbi.nlm.nih.gov/pubmed/22271820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.189910
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