Restoring allosterism with compensatory mutations in hemoglobin.

Abnormal human hemoglobins (HBs) with amino acid substitutions in the alpha 1 beta 2 interface have very high oxygen affinity and greatly reduced cooperativity in O2 binding compared to normal human Hb. In such abnormal Hbs with mutations at position beta 99, the intersubunit hydrogen bonds between...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Kim, H W, Shen, T J, Sun, D P, Ho, N T, Madrid, M, Tam, M F, Zou, M, Cottam, P F, Ho, C
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC45268/
https://ncbi.nlm.nih.gov/pubmed/7972099
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker