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Anti-Proliferative Actions of a Synthetic REV-ERBα/β Agonist in Breast Cancer Cells

REV-ERBα and REV-ERBβ are nuclear receptors that are ligand-dependent transcriptional repressors. Heme is the natural ligand for these receptors, but several synthetic agonists and antagonists have been designed recently. The gene that encodes REV-ERBα, NR1D1, is closely associated with ERBB2, the g...

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Vydáno v:Biochem Pharmacol
Hlavní autoři: Wang, Yongjun, Kojetin, Douglas, Burris, Thomas P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526361/
https://ncbi.nlm.nih.gov/pubmed/26074263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.06.010
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