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Characterization of the Core Mammalian Clock Component, NPAS2, as a REV-ERBα/RORα Target Gene
The mammalian clock is regulated at the cellular level by a transcriptional/translational feedback loop. BMAL1/CLOCK (or NPAS2) heterodimers activate the expression of the PERIOD (PER) and CRYPTOCHROME (CRY) genes acting as transcription factors directed to the PER and CRY promoters via E-box elemen...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975162/ https://ncbi.nlm.nih.gov/pubmed/20817722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.129288 |
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