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Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein

Nucleocytoplasmic trafficking of proteins/RNAs is essential to normal cellular function. Indeed, accumulating evidence suggests that cancer cells escape anti-neoplastic mechanisms and benefit from pro-survival signals via the dysregulation of this system. The nuclear exporter chromosome region maint...

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Détails bibliographiques
Publié dans:Pharmacol Ther
Auteurs principaux: Ishizawa, Jo, Kojima, Kensuke, Hail, Numsen, Tabe, Yoko, Andreeff, Michael
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526315/
https://ncbi.nlm.nih.gov/pubmed/26048327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2015.06.001
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