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Engineering chromosome region maintenance 1 fragments that bind to nuclear export signals

Chromosome region maintenance 1 (CRM1) exports nuclear export signal (NES) containing cargos from nucleus to cytoplasm and plays critical roles in cancer and viral infections. Biochemical and biophysical studies on this protein were often obstructed by its low purification yield and stability. With...

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Bibliographische Detailangaben
Veröffentlicht in:Protein Sci
Hauptverfasser: Lei, Yuqin, An, Qi, Zhang, Yuqing, Luo, Ping, Luo, Youfu, Shen, Xiaofei, Jia, Da, Sun, Qingxiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255508/
https://ncbi.nlm.nih.gov/pubmed/31495993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3724
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