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Engineering chromosome region maintenance 1 fragments that bind to nuclear export signals

Chromosome region maintenance 1 (CRM1) exports nuclear export signal (NES) containing cargos from nucleus to cytoplasm and plays critical roles in cancer and viral infections. Biochemical and biophysical studies on this protein were often obstructed by its low purification yield and stability. With...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Lei, Yuqin, An, Qi, Zhang, Yuqing, Luo, Ping, Luo, Youfu, Shen, Xiaofei, Jia, Da, Sun, Qingxiang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255508/
https://ncbi.nlm.nih.gov/pubmed/31495993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3724
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