Overexpression of DNA methyltransferase 1 (DNMT1) protein in astrocytic tumour and its correlation with O6-methylguanine-DNA methyltransferase (MGMT) expression

Background: The relationship between DNA methyltransferase (DNMT) and O6-methylguanine-DNA methyltransferase (MGMT) in mediating tumorigenesis is still poorly understood. This study was carried out to investigate a correlation between DNMT1 and MGMT immunoexpression in astrocytic tumour samples. Met...

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Bibliographic Details
Published in:Int J Clin Exp Pathol
Main Authors: Rahman, Wan Faiziah Wan Abdul, Rahman, Khairul Shakir Ab, Nafi, Siti Norasikin Mohd, Fauzi, Mohd Hashairi, Jaafar, Hasnan
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525821/
https://ncbi.nlm.nih.gov/pubmed/26261487
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