Disturbed Cholesterol Traffic but Normal Proteolytic Function in LAMP-1/LAMP-2 Double-deficient Fibroblasts
Mice double deficient in LAMP-1 and -2 were generated. The embryos died between embryonic days 14.5 and 16.5. An accumulation of autophagic vacuoles was detected in many tissues including endothelial cells and Schwann cells. Fibroblast cell lines derived from the double-deficient embryos accumulated...
محفوظ في:
| الحاوية / القاعدة: | Mol Biol Cell |
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| المؤلفون الرئيسيون: | , , , , , , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Cell Biology
2004
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452571/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15121881/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E04-02-0103 |
| الوسوم: |
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