Disturbed Cholesterol Traffic but Normal Proteolytic Function in LAMP-1/LAMP-2 Double-deficient Fibroblasts

Mice double deficient in LAMP-1 and -2 were generated. The embryos died between embryonic days 14.5 and 16.5. An accumulation of autophagic vacuoles was detected in many tissues including endothelial cells and Schwann cells. Fibroblast cell lines derived from the double-deficient embryos accumulated...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Eskelinen, Eeva-Liisa, Schmidt, Christine Katrin, Neu, Silja, Willenborg, Marion, Fuertes, Graciela, Salvador, Natalia, Tanaka, Yoshitaka, Lüllmann-Rauch, Renate, Hartmann, Dieter, Heeren, Jörg, von Figura, Kurt, Knecht, Erwin, Saftig, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC452571/
https://ncbi.nlm.nih.gov/pubmed/15121881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-02-0103
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados