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129-Derived Mouse Strains Express an Unstable but Catalytically Active DNA Polymerase Iota Variant
Mice derived from the 129 strain have a nonsense codon mutation in exon 2 of the polymerase iota (Polι) gene and are therefore considered Polι deficient. When we amplified Polι mRNA from 129/SvJ or 129/Ola testes, only a small fraction of the full-length cDNA contained the nonsense mutation; the maj...
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| Pubblicato in: | Mol Cell Biol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4525304/ https://ncbi.nlm.nih.gov/pubmed/26124279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00371-15 |
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