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Infrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation

Amyloids are insoluble protein fibrillar aggregates. The importance of characterizing their aggregation has steadily increased because of their link to human diseases and material science applications. In particular, misfolding and aggregation of the Josephin domain of ataxin-3 is implicated in spin...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Ruggeri, F. S., Longo, G., Faggiano, S., Lipiec, E., Pastore, A., Dietler, G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525161/
https://ncbi.nlm.nih.gov/pubmed/26215704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8831
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