Evolution of Conformation, Nanomechanics, and Infrared Nanospectroscopy of Single Amyloid Fibrils Converting into Microcrystals

Nanomechanical properties of amyloid fibrils and nanocrystals depend on their secondary and quaternary structure, and the geometry of intermolecular hydrogen bonds. Advanced imaging methods based on atomic force microscopy (AFM) have unravelled the morphological and mechanical heterogeneity of amylo...

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Veröffentlicht in:Adv Sci (Weinh)
Hauptverfasser: Adamcik, Jozef, Ruggeri, Francesco Simone, Berryman, Joshua T., Zhang, Afang, Knowles, Tuomas P. J., Mezzenga, Raffaele
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816722/
https://ncbi.nlm.nih.gov/pubmed/33511004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202002182
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