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Infrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation

Amyloids are insoluble protein fibrillar aggregates. The importance of characterizing their aggregation has steadily increased because of their link to human diseases and material science applications. In particular, misfolding and aggregation of the Josephin domain of ataxin-3 is implicated in spin...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ruggeri, F. S., Longo, G., Faggiano, S., Lipiec, E., Pastore, A., Dietler, G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525161/
https://ncbi.nlm.nih.gov/pubmed/26215704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8831
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