Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide.

The beta-amyloid (Abeta) peptide, a major component of senile plaques in Alzheimer's disease brain, has been shown previously to undergo a process of polymerization to produce neurotoxic forms of amyloid. Recent literature has attempted to define precisely the form of Abeta responsible for its...

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Main Authors: Ward, R V, Jennings, K H, Jepras, R, Neville, W, Owen, D E, Hawkins, J, Christie, G, Davis, J B, George, A, Karran, E H, Howlett, D R
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221046/
https://ncbi.nlm.nih.gov/pubmed/10794724
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