Cell-mediated degradation of type IV collagen and gelatin films is dependent on the activation of matrix metalloproteinases.

Por Atkinson, S J, Ward, R V, Reynolds, J J, Murphy, G
Publicado em 1992

Cell surface-mediated activation of progelatinase A: demonstration of the involvement of the C-terminal domain of progelatinase A in cell surface binding and activation of progelat...

Por Ward, R V, Atkinson, S J, Reynolds, J J, Murphy, G
Publicado em 1994

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and...

Por Murphy, G, Cockett, M I, Ward, R V, Docherty, A J
Publicado em 1991

The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloprot...

Por Ward, R V, Hembry, R M, Reynolds, J J, Murphy, G
Publicado em 1991

Interaction between tissue inhibitor of metalloproteinases-2 and progelatinase A: immunoreactivity analyses.

Por Fujimoto, N, Ward, R V, Shinya, T, Iwata, K, Yamashita, K, Hayakawa, T
Publicado em 1996

Tissue inhibitor of metalloproteinases and collagenase inhibitory activity in lung secretions from patients with chronic obstructive bronchitis: effect of corticosteroid treatment.

Por Burnett, D, Reynolds, J J, Ward, R V, Afford, S C, Stockley, R A
Publicado em 1986

The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metallopro...

Por Murphy, G, Willenbrock, F, Ward, R V, Cockett, M I, Eaton, D, Docherty, A J
Publicado em 1992

Common structural features determine the effectiveness of carvedilol, daunomycin and rolitetracycline as inhibitors of Alzheimer beta-amyloid fibril formation.

Por Howlett, D R, George, A R, Owen, D E, Ward, R V, Markwell, R E
Publicado em 1999

Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide.

Por Ward, R V, Jennings, K H, Jepras, R, Neville, W, Owen, D E, Hawkins, J, Christie, G, Davis, J B, George, A, Karran, E H, Howlett, D R
Publicado em 2000