Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1

Accumulating evidence indicates a role for Fc receptor (FcR)-mediated effector functions of antibodies, including antibody-dependent cell-mediated cytotoxicity (ADCC), in prevention of human immunodeficiency virus type 1 (HIV-1) acquisition and in postinfection control of viremia. Consequently, an u...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Virol
Κύριοι συγγραφείς: Gohain, Neelakshi, Tolbert, William D., Acharya, Priyamvada, Yu, Lei, Liu, Tongyun, Zhao, Pingsen, Orlandi, Chiara, Visciano, Maria L., Kamin-Lewis, Roberta, Sajadi, Mohammad M., Martin, Loïc, Robinson, James E., Kwong, Peter D., DeVico, Anthony L., Ray, Krishanu, Lewis, George K., Pazgier, Marzena
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2015
Θέματα:
Structure and Assembly
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524080/
https://ncbi.nlm.nih.gov/pubmed/26085162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01232-15
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