A molecular characterization of the agonist binding site of a nematode cys-loop GABA receptor

BACKGROUND AND PURPOSE: Cys-loop GABA receptors represent important targets for human chemotherapeutics and insecticides and are potential targets for novel anthelmintics (nematicides). However, compared with insect and mammalian receptors, little is known regarding the pharmacological characteristi...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Kaji, Mark D, Kwaka, Ariel, Callanan, Micah K, Nusrat, Humza, Desaulniers, Jean-Paul, Forrester, Sean G
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2015
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Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523332/
https://ncbi.nlm.nih.gov/pubmed/25850584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13158
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