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Molecular and pharmacological characterization of an acetylcholine-gated chloride channel (ACC-2) from the parasitic nematode Haemonchus contortus

Nematode cys-loop ligand-gated ion channels (LGICs) have been shown to be attractive targets for the development of novel anti-parasitic drugs. The ACC-1 family of receptors are a unique group of acetylcholine-gated chloride channels present only in invertebrates, and sequence analysis suggests that...

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Vydáno v:Int J Parasitol Drugs Drug Resist
Hlavní autoři: Habibi, Sarah A., Callanan, Micah, Forrester, Sean G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287471/
https://ncbi.nlm.nih.gov/pubmed/30266440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2018.09.004
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