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Molecular and pharmacological characterization of an acetylcholine-gated chloride channel (ACC-2) from the parasitic nematode Haemonchus contortus

Nematode cys-loop ligand-gated ion channels (LGICs) have been shown to be attractive targets for the development of novel anti-parasitic drugs. The ACC-1 family of receptors are a unique group of acetylcholine-gated chloride channels present only in invertebrates, and sequence analysis suggests that...

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Hlavní autoři: Sarah A. Habibi, Micah Callanan, Sean G. Forrester
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018-12-01
Edice:International Journal for Parasitology: Drugs and Drug Resistance
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2211320718301295
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