Investigating the function and possible biological role of an acetylcholine-gated chloride channel subunit (ACC-1) from the parasitic nematode Haemonchus contortus

The cys-loop superfamily of ligand-gated ion channels are well recognized as important drug targets for many invertebrate specific compounds. With the rise in resistance seen worldwide to existing anthelmintics, novel drug targets must be identified so new treatments can be developed. The acetylchol...

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Bibliografiska uppgifter
I publikationen:Int J Parasitol Drugs Drug Resist
Huvudupphovsmän: Callanan, Micah K., Habibi, Sarah A., Law, Wen Jing, Nazareth, Kristen, Komuniecki, Richard L., Forrester, Sean G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2018
Ämnen:
Articles from the scientific meeting: "Anthelmintics: From Discovery to Resistance III", pp. 494 - 628.
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287539/
https://ncbi.nlm.nih.gov/pubmed/30401619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2018.10.010
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