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Investigating the function and possible biological role of an acetylcholine-gated chloride channel subunit (ACC-1) from the parasitic nematode Haemonchus contortus

The cys-loop superfamily of ligand-gated ion channels are well recognized as important drug targets for many invertebrate specific compounds. With the rise in resistance seen worldwide to existing anthelmintics, novel drug targets must be identified so new treatments can be developed. The acetylchol...

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Pubblicato in:Int J Parasitol Drugs Drug Resist
Autori principali: Callanan, Micah K., Habibi, Sarah A., Law, Wen Jing, Nazareth, Kristen, Komuniecki, Richard L., Forrester, Sean G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287539/
https://ncbi.nlm.nih.gov/pubmed/30401619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2018.10.010
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