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Cyclic acetals as cleavable linkers for affinity capture
Labeling proteins with biotin is a widely used method to identify target proteins due to biotin’s strong binding affinity for streptavidin. Combined with alkyne-azide cycloaddition, which enables the coupling of probes to targeted proteins, biotin tags linked to an alkyne or azide have become a powe...
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| Publicado no: | Org Biomol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4523064/ https://ncbi.nlm.nih.gov/pubmed/26152933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob01056j |
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