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A Highly Selective Hsp90 Affinity Chromatography Resin with a Cleavable Linker

Over 200 proteins have been identified that interact with the protein chaperone Hsp90, a recognized therapeutic target thought to participate in non-oncogene addiction in a variety of human cancers. However, defining Hsp90 clients is challenging because interactions between Hsp90 and its physiologic...

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Detalhes bibliográficos
Main Authors: Hughes, Philip F, Barrott, Jared J, Carlson, David A, Loiselle, David R, Speer, Brittany L, Bodoor, Khaldon, Rund, Lauretta A, Haystead, Timothy A J
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345094/
https://ncbi.nlm.nih.gov/pubmed/22520629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.03.043
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