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The Charged Linker Region Is an Important Regulator of Hsp90 Function

Hsp90 is an ATP-dependent molecular chaperone which assists the maturation of a large set of target proteins. Members of the highly conserved Hsp90 family are found from bacteria to higher eukaryotes, with homologues in different organelles. The core architecture of Hsp90 is defined by the N-termina...

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Sonraí Bibleagrafaíochta
Main Authors: Hainzl, Otmar, Lapina, Maria Claribel, Buchner, Johannes, Richter, Klaus
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755663/
https://ncbi.nlm.nih.gov/pubmed/19553666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.031658
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