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The Charged Linker Region Is an Important Regulator of Hsp90 Function

Hsp90 is an ATP-dependent molecular chaperone which assists the maturation of a large set of target proteins. Members of the highly conserved Hsp90 family are found from bacteria to higher eukaryotes, with homologues in different organelles. The core architecture of Hsp90 is defined by the N-termina...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hainzl, Otmar, Lapina, Maria Claribel, Buchner, Johannes, Richter, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755663/
https://ncbi.nlm.nih.gov/pubmed/19553666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.031658
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