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Structure, Function, and Regulation of the Hsp90 Machinery
Heat shock protein 90 (Hsp90) is a molecular chaperone involved in the maturation of a plethora of substrates (“clients”), including protein kinases, transcription factors, and E3 ubiquitin ligases, positioning Hsp90 as a central regulator of cellular proteostasis. Hsp90 undergoes large conformation...
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| Publicado no: | Cold Spring Harb Perspect Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6719599/ https://ncbi.nlm.nih.gov/pubmed/30745292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a034017 |
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