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Structure, Function, and Regulation of the Hsp90 Machinery

Heat shock protein 90 (Hsp90) is a molecular chaperone involved in the maturation of a plethora of substrates (“clients”), including protein kinases, transcription factors, and E3 ubiquitin ligases, positioning Hsp90 as a central regulator of cellular proteostasis. Hsp90 undergoes large conformation...

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Foilsithe in:Cold Spring Harb Perspect Biol
Main Authors: Biebl, Maximilian M., Buchner, Johannes
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719599/
https://ncbi.nlm.nih.gov/pubmed/30745292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a034017
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