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Secondary Amino Alcohols: Traceless Cleavable Linkers for Use in Affinity Capture and Release

Capture and release of peptides is often a critical operation in the pathway to discovering materials with novel functions. However, the best methods for efficient capture impede facile release. To overcome this challenge, we report secondary amino alcohol-based linkers for release of peptides after...

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Publicado en:Angew Chem Int Ed Engl
Main Authors: Pomplun, Sebastian, Shugrue, Christopher R., Schmitt, Adeline M., Schissel, Carly K., Farquhar, Charlotte E., Pentelute, Bradley L.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485622/
https://ncbi.nlm.nih.gov/pubmed/32227406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202003478
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