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Traceless parallel peptide purification by a first-in-class reductively cleavable linker system featuring a safety-release

Hundreds of peptides can be synthesized by automated parallel synthesizers in a single run. In contrast, the most widely used peptide purification method – high-pressure liquid chromatography (HPLC) – only allows one-by-one processing of each sample. The chromatographic purification of many peptides...

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Publicado en:Chem Sci
Autores principales: Zitterbart, Robert, Berger, Nadja, Reimann, Oliver, Noble, Gavin T., Lüdtke, Stephan, Sarma, Dominik, Seitz, Oliver
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society of Chemistry 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179278/
https://ncbi.nlm.nih.gov/pubmed/34164003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc06285e
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