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Conformational kinetics reveals affinities of protein conformational states

Most biological reactions rely on interplay between binding and changes in both macromolecular structure and dynamics. Practical understanding of this interplay requires detection of critical intermediates and determination of their binding and conformational characteristics. However, many of these...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Daniels, Kyle G., Suo, Yang, Oas, Terrence G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522757/
https://ncbi.nlm.nih.gov/pubmed/26162682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502084112
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